Description
Product Characteristics:
Aliases: Alpha tropomyosin 3 antibody, Alpha tropomyosin slow skeletal antibody, CFTD antibody, Cytoskeletal tropomyosin TM30 antibody, FLJ41118 antibody, gamma TM antibody, Gamma tropomyosin antibody, Gamma-tropomyosin antibody, Heat stable cytoskeletal protein 30 kDa antibody, hscp30 antibody, hTM30nm antibody, hTM5 antibody, hTMnm antibody, MGC102590 antibody, MGC14582 antibody, MGC3261 antibody, MGC72094 antibody, NEM1 antibody, OK/SW-cl.5 antibody, OTTHUMP00000034019 antibody, OTTHUMP00000034171 antibody, OTTHUMP00000034172 antibody, TM 5 antibody, TM-5 antibody, TM3 antibody, TM30 antibody, TM30nm antibody, TM5 antibody, Tm5NM antibody, Tpm 5 antibody, TPM3 antibody, TPM3/NTRK1 FUSION GENE, INCLUDED antibody, TPM3_HUMAN antibody, Tpm5 antibody, TPMsk3 antibody, TRK antibody, TRK ONCOGENE, INCLUDED antibody, Trop 5 antibody, Tropomyosin 3 antibody, Tropomyosin 3 gamma antibody, Tropomyosin 5 antibody, Tropomyosin alpha 3 chain antibody, Tropomyosin alpha-3 chain antibody, Tropomyosin gamma antibody, Tropomyosin-3 antibody, Tropomyosin-5 antibody
Target Information: This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]